International Journal of Applied Pharmaceutical and Biological ResearchJournal of Applied Pharmaceutical and Biological Research (IJAPBR) is an international bimonthly journal, constitutes and covers integral and fundamental aspects of pharmaceutical, Environmental chemical and medical sciences. It is a peer reviewed journal focus to communicate high quality research articles, reviews and general articles in the field of applied pharmaceutical, Environmental and chemical sciences. IJAPBR is the platform established with the aim of motivating the students and such personal in the pharmaceutical and applied research and developments.
The journal publishes research reports in the form of original articles or short communications on most aspects of applied sciences, with strong emphasis on originality and scientific quality. IJAPBR deals with original research work that contributes significantly to further the scientific knowledge in medical, health sciences, life sciences and other pharmaceutical sciences (Pharmaceutical Technology, Pharmaceutics, Bio pharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics including biotechnology, cell and molecular biology, microbiology).
Although IJAPBR is primarily devoted to original research papers, the journal particularly welcomes reviews on current topics of relevant fields, short communications, reviews and notes dealing with entire aspects of Chemical, Environmental, Medical and Pharmaceutical sciences.
2. Effectiveness of Guyabano Fruit (Annona Muricata) and Pineapple (Ananas Comosus) Extract in the Fermentation Process of Vinegar
Objectives: This study aimed to determine the effectiveness of guyabano fruit and pineapple extract in the fermentation process of vinegar. Methodology: Pineapple and guyabano fruits were gathered from Alilem, Ilocos Sur, Philippines. Three treatments and three replications were formulated, respectively.
Phil Dominic B. Bandiola, Vincent Castro, Teresa May B. Bandiola
IJAPBR, 2017; 2(3): 7-10
3. Evaluation of Novel Heterocyclic Compounds Containing Pyrimidine and Thiazolidinone Rings
A new class of heterocyclic compounds containing pyrimidine and thiazolidinone rings was screened for antidiabetic, anti-inflammatory and antioxidant activity by alpha-amylase inhibition, inhibition of protein denaturation and hydrogen peroxide radical scavenging activity respectively by using in vitro method.
Ganesh S Andhale*, Sapana M Nagare, DP Venkatesh, Rajaganapathy KP
IJAPBR, 2017; 2(3):11-17
5. Quantification of Phenolic Compounds in Herbal Raw Materials Using Hptlc
The research work envisages quantification of phenolic compounds using High Performance Thin Layer Chromatography in medicinally important plants Ficus lacor fruits, Caesalpinia bonduc bark, Althaea officinalis seed.
PA Agrawala*, MS Akhadea and KS Laddhaa
IJAPBR, 2017; 2(3): 24-27
6. Quantification of Steroids and Triterpenoids From Indian Medicinal Plants by Hplc
The study aimed at identification and quantification of phytoconstituents present in the biologically active roots of Pavetta tomentosa, leaves of Commiphora caudata and rhizomes of Maranta arundinacea. A reversed-phase High Performance Liquid Chromatography (HPLC) method with a single solvent system has been used for quantification of different steroids and triterpenoids.
MS Akhade a*, PA Agrawala and KS Laddhaa
IJAPBR, 2017; 2(3): 28-32
7. In Vitro Determination of Cytotoxic Activity of Fucoidan Extract of Sargassum Serratifolium C. Agardh (Aragan) Against Mcf7 (Human Breast Cancer) Cell Line
Objectives: This study aimed to determine the cytotoxic property of the fucoidan extract of Sargassum serratifolium C. Agardh using MTT assay, Allium cepa (Onion) genotoxicity test, and Artemia salina (Brine shrimp) lethality test.
Jessica Joyce A. Duque*, Carmella V. Kapangyarihan, Charlene B. Lorenzo1, Paulene A. Sernada, Keesha T. Vergara, Albeine Grace D.C. Viliran, Dr. Angelita A. Rodriguez1, Juneve F. Tejada and Teresa May B. Bandiola
IJAPBR, 2017; 2(3): 33-45
8. Study of Cardioprotective and Antihypertensive Effects of Cardonarc Syrup-an Ayurvedic Proprietary Medicine in Fructose Induced Hypertension in Rats.
An experimental study was conducted to evaluate the antihypertensive, antilipidemic and cardioprotective potentials of Cardonarc syrup- an Ayurvedic proprietary medicine in fructose induced hypertensive and cardiotoxic rats. Albino Sprague Dawley rats (24 male) were equally divided into 4 groups. Group I served as normal control.
Kallolika Mondal, Shivalinge Gowda Kp*, Suman Manandhar, Sunitha R Joshi, Swapna Ranjitha, Elumalai P.
IJAPBR, 2017; 2(3): 46-58
9. Validated Rp - Hplc Method for the Estimation of Flucloxacillin Sodium in Tablet Formulations
A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Flucloxacillin Sodium in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.0 ml/min was employed on symmetry Bondpeak C18 10 µm (3.9 x 300 mm) at ambient temperature. The mobile phase consisted of Acetonitrile: 0.0.1M Phosphate buffer in the ratio of 35:65/v/v. The UV detection wavelength was 273nm and 10µl sample was injected.
V. D. N. Kumar Abbaraju* & V. Sreeram
IJAPBR, 2017; 2(3): 59-66
10. A Review on Stability Studies of Pharmaceutical Products
Stability studies are a routine procedure for ensuring the maintenance of pharmaceutical product safety, quality and efficacy throughout the shelf life. These pharmaceutical products are followed by the guidelines issued by Regulatory bodies like ICH, WHO or other regulatory agencies. Stability testing provides evidence that the quality of a drug product under the influence of various environmental factors changes with time.
Suthar Narayan*, Choudhary Manupriya
IJAPBR, 2017; 2(3): 67-75
11. Self-emulsifying Drug Delivery System: a Novel Drug Delivery Systems
In modern drug discovery techniques, there has been a consistent increase in the number of poor water soluble drug candidate compounds, and currently more than 50% of new pharmacologically active chemical entities are lipophilic and exhibit poor water solubility. Self-emulsifying drug delivery (SEDDS) is the one of the method for the improvement of oral bioavailability. SEDDS are the isotropic mixtures of oils, surfactants, solvents and co-solvents.
Choudhary M.*, Saurabh S.S., Pareek A. and Rathore K.S.
IJAPBR, 2017; 2(3):76-83