Abstract 09 V1 I1

Solvent anti solvent precipitation Method are used. In this Carbamazepine was dissolved in the solvent (ethanol) at concentrations ranging from 5 to 15 mg/ml. The Purpose of the present work is to enhance solubility of carbamazepine a class II drug by Nano suspensions technology. In this Carbamazepine was dissolved in the solvent (ethanol) at concentrations ranging from 5 to 15 mg/ml.

The experimental results had shown promising observations in terms of pH, drug content, and entrapment efficacy and % transmittance. Consequently Nano suspensions represent a promising alternative to current delivery systems aiming to improve the biopharmaceutical performance of drugs with low water solubility. The polymer can serve as potential polymer for formulating various drug loaded Nano suspensions.

Key words: Carbamazepine, Nanoparticles, Modified Precipitation method.