Abstract 01 V1 I5

Malaria, one of the most widespread diseases, is caused by a plasmodium parasite and it infects several hundred million people each year, results in several million deaths annually. Because there are four different species of protozoa that cause malaria, no one antimalarial drug is effective against all four species. In this computational research investigation, we performed In-silico pharmacokinetic, bioactivity and toxicity study of some selected antimalarial agents. To design a new molecule having good pharmacological profile, this study will provide the lead information.

Key-words: TPSA, GPCR, ADMETox, nON.