The synthesis and characterization of new coordination compounds of Ni (II), Cu (II) and Fe (II) with Schiff base derived from salicylaldehyde and aniline is reported. The ligand molecule appears to be bound to the transition metals through oxygen and nitrogen atoms. Their structures have been characterized by elemental analysis and bonding in these complexes is discussed in terms of IR Spectral study. The spectroscopic results obtained are in full agreement with the proposed 2:1 and 1:2 stoichiometries.
The infrared spectra of complexes display the complexation behavior of the Schiff base towards Ni (II), Cu(II) and Fe (II) ions and shows that they possesses square planar and trigonalbipyramidal geometry. The metal complexes soluble in DMSO have been tested against various Gram Positive and Gram negative bacteria. The results revealed that the complexes show promising to significant activity against Gram positive as well as Gram negative bacteria. The synthesized Schiff base and complexes were also exposed to different fungi in order to establish their antifungal activity. The copper complex exhibit promising activity against all fungi, while the complexes of Ni(II) and Fe(II) shows significant activity.
Keywords: Heavy metals, Schiff base, Antibacterial activity, Antifungal activity.