Volume 1 Issue 5 2016

Research Articles

1. In Silico Adme, Bioactivity and Toxicity Analysis of Some Selected Antimalarial Agents

Malaria, one of the most widespread diseases, is caused by a plasmodium parasite and it infects several hundred million people each year, results in several million deaths annually. Because there are four different species of protozoa that cause malaria, no one antimalarial drug is effective against all four species.

Neeraj Kumar et al IJAPBR,
2016; 1(5):1-8


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2. Consultation-liaison Approach for the Management of Psychiatric Manifestations in Inpatients of Neurology and Neurosurgery Wards

Background: Psychiatric manifestations in patients admitted in neurology and neurosurgery wards are now being increasingly recognized as important causes of morbidity and mortality. Materials and method: We studied the psychiatric manifestations for referral (N = 46) to consultation-liaison psychiatry services from neurology/neurosurgery between January 2016 and March 2016 using structured clinical proforma.

Nimmi Jose et al IJAPBR,
2016; 1(5):9-13


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3. Inoculation of Pongamia Pinnata With Phosphate Solubilizing Fungi: Effect on Plant Growth and Transplantation Establishment

Pongamia pinnata is well known forest tree speices having medicinal and biofuel properties. It is slow growing and seed dormancy is major constraints behind its large scale propagation. Micorbial inoculations are known to enhance the plant growth and productivity on is application of host rhizosphere. In view, a pot culture experiment was carried out on Pongamia pinnata for which 30 days old seedlings were raised from freshly collected seeds and transplanted in the poly pots containing red laterite soil and subsequently supplemented with 7 days old liquid culture of six different pretested phosphate solubilising fungi.

S. R. Nayak et al IJAPBR,
2016; 1(5):14-21


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4. Genetic Diversity and Relationship of Selected Cultivars of Rice, Oryza Sativa L. Using Random Amplified Polymorphic Dna (Rapd) Markers

The genetic diversity in 26 selected cultivars of rice, Oryza sativa L. using 20 decamer random primers. Out of 20, 15 RAPD primers revealed polymorphism while the remaining 5 primers showed no reaction. The primers produced a total of 71 bands of which 66 were polymorphic (95.2%). The number of polymorphic fragments for each primer varied from 1to3 with an average of 2.53 polymorphic fragments. The primer OPA-19 produced the maximum number of polymorphic bands.

B.K. Chikkswami and R.C. Paramanik IJAPBR,
2016; 1(5):22-28


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Review Articles

1. The Failure of Bacillus Thuringiensis Biotechnology: a Review

There is a new resolve, provoked by recent hikes in food prices around the world, to increase global food production in order to feed a rapidly growing population. In response to this, the biotechnology industry has made optimistic claims about the ability of genetically engineered (GE) crops—in which the plant DNA is changed using spliced genes that are often from unrelated organisms—to substantially increase farmers’ yields. Agricultural biotechnology has shown to increase crop production by seven- to tenfold in some developing countries, far beyond the production capabilities of traditional agriculture. Agricultural biotechnology is moving beyond input traits and is focused on delivering consumer health benefits. Over 10 new soybean varieties with human health benefits moving toward commercialization.

Afolabi Olubunmi IJAPBR,
2016; 1(5):29-33


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2. A Review on Sglt-2 Inhibitors

After metabolism of carbohydrate, glucose is filtered in the glomerular and then it is almost completely reabsorbed into circulation from the proximal renal tubules. S1 segment of the proximal tubule contains sodium-glucose co-transporter-2 (SGLT-2), which is responsible for the majority of glucose reabsorption. Some molecules which have property of inhibiting SGLT-2 have been reported in literature few of them reached in phase III of clinical trial. These agents reduce glucose reabsorption and increase urinary excretion of glucose and could be a novel alternative for the existing anti-diabetic agents in the market.

Hamdani Kulsum et al IJAPBR,
2016; 1(5):34-44


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3. Aristolochia Bracteata (Aristolochiaceae) Pharmacological Review

Aristolochia bracteolata is a shrub distributed throughout India, belongs to the family Aristolochiaceae. It is used in traditional medicines as a gastric stimulant and in the treatment of cancer, lung inflammation, dysentery and snakebites. In the indigenous system of medicine, the plant was used as purgative, antipyretic & anti-inflammatory agents. Its leaves are bitter and antihelmintic, antiulcer, antiplasmodial and are medicinally important.

R. R. Raja and P.S. Pandiyan IJAPBR,
2016; 1(5):45-50


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