Volume 2, Issue 2, 2017

Call for Manuscripts for Volume 2, Issue 2, 2017 (Releasing on May.31, 2017)

Research Articles

1. Physico-chemical and Microbiological Studies of Drinking Water From Mauritius

Access to safe drinking water is a fundamental requirement for good health and is also a human right. The monitoring of water supplies for the detection of faecal pollution is an important aspect for the detection of pathogenic bacteria, responsible for diseases such as gastroenteritis, cholera and bacillary dysentery thus representing serious health hazards.

Anjelee Ragoobur, Minu Gupta Bhowon, and Sabina Jhaumeer Laulloo*
IJAPBR, 2017; 2(2):1-10

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2.Stability Indicating New Rp-hplc Method for the Determination of Rosuvastatin Calcium in Pure and Tablets Dosage Forms

A new, specific, precise, simple, and accurate RP-HPLC method is developed and validated for the determination of Rosuvastatin calcium (ROS-Ca) in pure and tablets dosage forms. The method is performed on the Agilent Eclipse XDB C8 column (250 mm X 4.6 mm, 5μm particle size, using buffer solution of pH 4.5 containing 0.05M sodium dihydrogen phosphate.

Mohamed El-Kassem M Hassouna*, Hafsa Omar Salem
IJAPBR, 2017; 2(2):11-27

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3. U.v. Spectrophotometric Method for Estimation of Venlafaxine Hcl in Bulk and Formulation

Three simple, precise and economical UV methods have been developed for estimation of Venlafaxine HCl in single component. Venlafaxine HCl has the absorbance maximum in zero order spectrum (Method A) is 273.5nm. First Order derivative (Method B) was applied for the analysis of Venlafaxine HCl at 263.5nm.

Daswadkar S.C. *, Gajale V. N., Shevkar C. D., Phadtare G. A., Sonawane C. S.
IJAPBR, 2017; 2(2):28-33

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4.In-vitro Investigation of Biological Activity of Aerial Part of Syzygium Cumini

Plants parts and plant products of all the descriptions, particularly those with medicinal properties, are invariably used as principal components or ingredients of various traditional medicines. The ancient time of modern age the race successfully used plants and plant products as therapeutics tools for fitting against disease and various other health hazards.

Azima Sultana Julie, TanjinaSultana, Farhina Rahman Laboni, Samira Karim and Zubair Khalid Labu*
IJAPBR, 2017; 2(2):34-38

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5. Effect of Coleus Amboinicus Leaf Extract and Oil on Clinical Isolates of Pseudomonas and Proteus

Herbal plant extracts are potential sources of antibiotic prototypes. Numerous studies have demonstrated the antimicrobial activity of active compounds in herbal plant extracts against commonly found bacteria. Hence, the search for novel plants with medicinal value that are potential alternatives to currently used antibiotics (tetracycline, chloramphenicol etc.) is an important area of research. In this paper, we investigate the antimicrobial activity of Coleus amboinicus or Plectranthus amboinicus by preparing an aqueous and hexane extract and leaf oil and testing against clinical isolates of Pseudomonas aeruginosa and Proteus mirabilis.

Vasavi Dathar1* and Afrojahan2
IJAPBR, 2017; 2(2):39-47

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6.formulation and Evaluation of Fast Dissolving Film of Etophylline

Recently, fast dissolving films are gaining interest as an alternative of fast dissolving tablets. The films are designed to dissolve upon contact with a wet surface, such as the tongue, within a few seconds, meaning the consumer can take the product without need for additional liquid.

Sandip Buddhadev*1 Sheetal Buddhadev2
IJAPBR, 2017; 2(2):48-55

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Review Articles

7. Nanoparticles as Antimicrobial Agents Against Medically Important Pathogens

Nanotechnology is gaining tremendous impetus in the present century due to its capability of modulating metals into their nano size, which drastically changes the chemical, physical and optical properties of metals. The extremely small size of nanoparticles help them to occupy a greater surface area and hence a better accessibility and targeted action. Nanoparticles can overcome existing drug resistance mechanisms, including decreased uptake and increased efflux of drug from the microbial cell, biofilm formation, and intracellular bacteria. Nanoparticles can target antimicrobial agents to the site of infection, so that higher doses of drug are given at the infected site, thereby overcoming resistance.

Priyanka Khati
IJAPBR, 2017; 2(2):56-66

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Prebiotics are non-digestible food supplements which continue to gain interest due to various health promising benefits. They change the gut microbiota and prevent common disorders such as obesity, cancer, hypertension, inflammatory bowel disease, diarrhea, constipation, osteoporosis, cardiovascular disorders, diabetes, hypertension, hypercholesterolemia and various allergies.

Yogita Lugani, Balwinder Singh Sooch
IJAPBR, 2017; 2(2):67-73

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